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Stem Cell Therapy for Inclusion Body Myositis in Delhi, India - Stem Cell Therapy Hospital & Centre In Delhi India
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    Stem Cell Therapy for Inclusion Body MyositisStem Cell Therapy for Inclusion Body Myositis in Delhi, India

    Inclusion Body Myositis (IBM) is an uncommon, degenerative, autoimmune disorder affecting muscles, which is mostly an adult muscle disease usually seen in people over 50.

    The muscle weakness, atrophy, and difficulty in swallowing due to the involvement of the pharynx and laryngopharynx muscles are symptoms of IBM, which starts slowly and progresses gradually with time. Frequently, the use of corticosteroids and other immunosuppressive drugs for treatment is ineffective in stopping the progression of muscle wasting.

    Consequently, researchers are more attracted to the possibility of prescribed and alternative treatment of IBM by the use of stem cell therapy, which is one of the new and cutting-edge therapies that have been clinically hypothesized to bring about muscle regeneration and to reduce inflammation and immune activation.

    Patients from all over the world who are in need of stem cell treatment have Delhi, India, on their lists as their top choice for a quick and effective solution. It especially holds true for those suffering from neurological and muscular diseases like IBM.

    Numerous hospitals and research institutes in New Delhi have made it possible for patients to receive the latest stem cell therapies that can alleviate the symptoms of their underlying disorders and help them attain a better quality of life.

    Understanding Inclusion Body Myositis (IBM)

    What is inclusion body myositis?

    Inclusion body myositis (IBM) is a progressive inflammatory myopathy characterized by muscle weakness, muscle wasting, and muscle cells containing abnormal protein aggregates referred to as inclusion bodies. It mainly affects the muscles of the thighs, forearms, and the muscles of swallowing. The presence of IBM leads to progressive difficulty with standing, walking, and swallowing over time. The cause of IBM is poorly understood, although possible factors include genetic predisposition, attack of the muscle by an autoimmune process, and aging.

    Signs of IBM

    Signs tend to occur gradually and may include:

    • Muscle weakness in the thighs and forearms.
    • Difficulty standing up from a seated position, walking up stairs, and/or lifting things.
    • Muscle wasting (atrophy) and loss of strength.
    • Difficulties with swallowing (dysphagia) leading to aspiration pneumonia.
    • Stiffness and aching in joints.

    In the later stage, patients may be wheelchair-bound and/or in need of respiratory assistance.

    Standard Management for IBM

    There is no cure for IBM, and the treatments that are available are symptomatic:

    • Corticosteroids: There is limited effectiveness, and the long-term side effects are significant.
    • Immunosuppressive Agents: Methotrexate and azathioprine are often ineffective.
    • Physical Therapy: Designed to maintain mobility, strength, and functional skills
    • Supportive Care: Dietary changes, use of ventilators, or use of mobility devices

    Based on so little success with standard treatments and their medicating strategies, stem cell therapy is being investigated.

    Stem Cell Therapy: A Promising Approach for IBM

    How Stem Cells Function in IBM

    Stem cells can regenerate damaged muscle by:

    • Differentiating into new muscle cells to replace damaged muscle tissue.
    • Modulating the immune system response to decrease inflammation.
    • Secreting growth factors, which aid in tissue repair.
    • Decreasing fibrosis (muscle scarring) to increase function.
    • Protecting nerves associated with swallowing and breathing.

    Types of Stem Cells Used

    • Mesenchymal Stem Cells (MSCs): Located in bone marrow and adipose tissue, MSCs are known for their ability to regulate inflammation and promote repair.
    • Satellite Cells: The natural muscle stem cells that contribute to the regeneration of muscle fibers.
    • Induced Pluripotent Stem Cells (iPSCs): Cells that can be derived from patients and then reprogrammed to be any cell type, reducing the chance of rejection.
    • Embryonic Stem Cells (ESCs): Versatile cell type associated with ethics and increased risk of tumors.
    • Adipose-Derived Stem Cells (ADSCs): Stem cells that come from adipose tissue that can cause muscle regeneration.

    Stem Cell Therapy for IBM in New Delhi, India

    In New Delhi, there are a plethora of health systems with reputable hospitals that provide state-of-the-art stem cell treatments:

    • Medtravellers: Specialized in custom MSC-based treatments that take into account the disease severity and patients’ illnesses. 
    • Max Healthcare: Regenerative treatment for the management of musculoskeletal and neurologic illness. 
    • Fortis Healthcare: Well known for its expertise and advanced technology for treating degenerative diseases. 
    • AIIMS (All India Institute of Medical Sciences): A preeminent research institute that conducts clinical trials on stem cell therapies. 
    • Indraprastha Apollo Hospitals: Offers expertise on regenerative medicine and is an institute of education and research. 

    Patients get access to very talented physicians, level I accreditation, and seamless care.

    Advantages of Stem Cell Therapy for IBM in India

    • Affordability: Complex treatments are substantially less expensive than the pricing in Western nations. 
    • Highly skilled personnel: Facilities utilize protocols that have been validated through science, evidence-based protocols at facilities with board-certified specialists with training from abroad.
    • Full medical tourism: Facilities help with visa processing, accommodations, and telehealth follow-up appointments.
    • Better demonstrated outcomes: Patients often report their disease is stabilized and feel an improved quality of life.

    Conclusion

    Stem cell treatment is now available in New Delhi for patients with inclusion body myositis, a disease that is difficult and progressive when standard treatments are inadequate for treatment or delivery. Stem cells have the potential to regenerate muscle, reduce inflammation, and restore neuromuscular function. The combination of the best medical experts available, the costs to patients, and patient centered care reflects India’s attractiveness as a place to receive treatment.

    FAQs

    1. What is Inclusion Body Myositis (IBM)?

    Inclusion Body Myositis (IBM) is a rare autoimmune muscle disease that causes progressive muscle weakness and muscle wasting, primarily affecting older adults.

    2. How can stem cell therapy help in the treatment of IBM?

    Stem cells can regenerate damaged muscle fibers, help reduce inflammation, and facilitate tissue repair as a possible way to slow progression of the disease.

    3. Which stem cells may be used for IBM treatment?

    Stem cells that may be used for treatment of IBM include mesenchymal stem cells (MSCs), satellite cells, induced pluripotent stem cells (iPSCs), embryonic stem cells (ESCs), and adipose-derived stem cells (ADSCs).

    4. What are the advantages of seeking stem cell treatment for IBM in Delhi, India?

    There are many advantages of seeking stem cell treatment for IBM in New Delhi, India, such as using advanced technology in internationally accredited hospitals, cooperation with trained doctors at affordable prices, and comprehensive service and support for international patients.